Protein That Functions in Normal Breast May Also Contribute to Breast Cancer Metastasis
By Elsevier Health Sciences. — From sciencedaily.com February 23, 2012 460 2
The trefoil factor 3 (TFF3) protein protects and maintains the integrity of the epithelial surface in the normal breast. New research has found that while TFF3 protein expression is higher in well-differentiated low grade tumors and therefore associated with features of a good prognosis, it has a more sinister role in breast cancer invasion and metastasis. The report is published in the March issue of The American Journal of Pathology.