Protein That Functions in Normal Breast May Also Contribute to Breast Cancer Metastasis

By Elsevier Health Sciences. — From sciencedaily.com Published at February 23, 2012 Views 346 Likes 2

The trefoil factor 3 (TFF3) protein protects and maintains the integrity of the epithelial surface in the normal breast. New research has found that while TFF3 protein expression is higher in well-differentiated low grade tumors and therefore associated with features of a good prognosis, it has a more sinister role in breast cancer invasion and metastasis. The report is published in the March issue of The American Journal of Pathology.

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